Shinsuke Nakamura Selected Research

Papilledema

1/2022	Efficacy of an Anti-Semaphorin 3A Neutralizing Antibody in a Male Experimental Retinal Vein Occlusion Mouse Model.
1/2021	Creation of Retinal Vein Occlusion Model in Cynomolgus Monkeys and Determination of its Pathological Features.
1/2021	Oral administration of NSP-116, a free radical scavenger, suppresses the symptoms of retinal vein occlusion in the murine model.
1/2021	Establishment of a pigmented murine model abundant with characteristics of retinal vein occlusion.
1/2021	Excess adiponectin in eyes with progressive ocular vascular diseases.
1/2019	Oral and ocular administration of crocetin prevents retinal edema in a murine retinal vein occlusion model.
6/2018	Effects of ripasudil, a ROCK inhibitor, on retinal edema and nonperfusion area in a retinal vein occlusion murine model.
1/2018	Pathophysiological Role of VEGF on Retinal Edema and Nonperfused Areas in Mouse Eyes With Retinal Vein Occlusion.

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Shinsuke Nakamura Research Topics

Disease

10	Ischemia 01/2022 - 12/2011
9	Choroidal Neovascularization 08/2021 - 09/2014
8	Macular Degeneration (Age-Related Maculopathy) 02/2022 - 02/2011
8	Retinal Vein Occlusion 01/2022 - 01/2018
8	Papilledema 01/2022 - 01/2018
8	Retinal Neovascularization 01/2021 - 01/2010
7	Brain Injuries (Brain Injury) 02/2022 - 11/2018
7	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022 - 02/2011
6	Neoplasms (Cancer) 04/2022 - 01/2013
5	Glioblastoma (Glioblastoma Multiforme) 04/2022 - 11/2019
5	Hypoxia (Hypoxemia) 01/2022 - 06/2012
5	Ganglion Cysts (Ganglion) 01/2021 - 03/2013
4	Macular Edema 01/2022 - 01/2017
4	Retinal Degeneration 10/2021 - 01/2018
4	Atrophy 01/2021 - 06/2013
4	Hematoma 01/2021 - 01/2019
4	Blindness (Hysterical Blindness) 01/2021 - 02/2011
4	Intracranial Hemorrhages (Intracranial Hemorrhage) 11/2020 - 01/2019
4	Reperfusion Injury 01/2020 - 08/2013
3	Fibrosis (Cirrhosis) 01/2022 - 07/2018
3	Mitochondrial Diseases (Mitochondrial Disease) 12/2021 - 01/2020
3	Inflammation (Inflammations) 07/2021 - 10/2012
3	Pathologic Neovascularization 01/2021 - 06/2012
3	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 12/2020 - 07/2018
3	Infarction (Infarctions) 01/2020 - 11/2019
2	Infections 02/2022 - 10/2012
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 02/2022 - 01/2022
2	Edema (Dropsy) 01/2022 - 01/2021
2	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2021 - 01/2019
2	Hemorrhage 01/2021 - 11/2020
2	Hemorrhagic Stroke 01/2021 - 11/2019
2	Stroke (Strokes) 01/2020 - 11/2019
2	Ischemic Stroke 01/2020 - 11/2019
2	Brain Ischemia (Cerebral Ischemia) 01/2020 - 07/2018
2	Brain Edema (Cerebral Edema) 01/2020 - 12/2018
2	Glaucoma 06/2018 - 01/2018
2	Retinal Perforations 01/2017 - 05/2011
2	Retinopathy of Prematurity (Retrolental Fibroplasia) 01/2012 - 02/2011
2	Hyperoxia 05/2011 - 01/2010
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 03/2022
1	Lysosomal Storage Diseases (Lysosomal Storage Disease) 03/2022
1	COVID-19 02/2022
1	Neovascular Glaucoma 01/2022
1	Cognitive Dysfunction 01/2022
1	Retinal Diseases 01/2022
1	Ocular Hypertension (Glaucoma, Suspect) 01/2022
1	Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy) 10/2021
1	Alzheimer Disease (Alzheimer's Disease) 02/2021
1	Dry Eye Syndromes (Dry Eye Syndrome) 01/2021
1	Eye Diseases (Eye Disease) 01/2021

Drug/Important Bio-Agent (IBA)

22	Retinaldehyde (Retinal)IBA 02/2022 - 02/2011
13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 06/2012
9	Oxygen (Dioxygen)IBA 01/2021 - 02/2011
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2013
5	ProgranulinsIBA 03/2022 - 01/2019
4	Neuroprotective AgentsIBA 01/2022 - 09/2014
4	Free Radical ScavengersIBA 01/2021 - 09/2010
4	Pharmaceutical PreparationsIBA 01/2021 - 01/2019
3	AntioxidantsIBA 12/2021 - 11/2018
3	Collagenases (Collagenase)FDA Link 01/2021 - 11/2018
3	IronIBA 01/2021 - 01/2019
2	nafamostatIBA 02/2022 - 01/2022
2	Therapeutic UsesIBA 12/2021 - 11/2020
2	Chelating AgentsIBA 01/2021 - 11/2020
2	4- (4- acetylpiperazin- 1- yl)- 2- (1H- imidazol- 1- yl)anilineIBA 01/2021 - 11/2019
2	astaxanthine (astaxanthin)IBA 09/2020 - 11/2018
2	adonixanthinIBA 09/2020 - 11/2018
2	Temozolomide (Temodar)FDA LinkGeneric 03/2020 - 11/2019
2	Levetiracetam (Keppra)FDA LinkGeneric 01/2020 - 07/2019
2	Hemoglobins (Hemoglobin)IBA 01/2020 - 11/2018
2	Peptides (Polypeptides)IBA 01/2020 - 05/2011
2	trans-sodium crocetinate (crocetin)IBA 01/2019 - 03/2013
2	Protein Isoforms (Isoforms)IBA 01/2018 - 01/2017
2	EdaravoneIBA 01/2016 - 09/2010
1	Sodium-Glucose Transporter 2 InhibitorsIBA 04/2022
1	CanagliflozinIBA 04/2022
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2022
1	Neutralizing AntibodiesIBA 01/2022
1	Fibronectins (Fibronectin)IBA 01/2022
1	Thrombin FDA Link 01/2022
1	afliberceptIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Vascular Endothelial Growth FactorsIBA 01/2022
1	Scopolamine (Hyoscine)FDA Link 01/2022
1	Semaphorin-3AIBA 01/2022
1	3-nitropropionic acidIBA 12/2021
1	Mitochondrial DNA (mtDNA)IBA 10/2021
1	RotenoneIBA 10/2021
1	Activating Transcription Factor 4IBA 08/2021
1	asaroneIBA 02/2021
1	Ranibizumab (Lucentis)FDA Link 01/2021
1	Deferasirox FDA Link 01/2021
1	AdiponectinIBA 01/2021

Therapy/Procedure

10	Lasers (Laser) 07/2021 - 09/2014
7	Oral Administration 01/2022 - 01/2019
7	Therapeutics 01/2022 - 09/2014
3	Intravitreal Injections 01/2021 - 01/2017
3	Ligation 10/2013 - 12/2011
1	Extracorporeal Membrane Oxygenation 02/2022
1	Intravenous Injections 01/2021